I am a baseball fan, so I love to jump to my feet and cheer a home run.
I just now opened up the August 11 issue of the New England Journal of Medicine. There is a clear public health homerun in the lead article (Prevention of HIV-1 infection with early antiretroviral therapy. Cohen MS et al. NEJM 2011; 365:493-505).
This paper describes a randomized controlled trial done in 9 countries. Partners who were discordant for HIV infection (i.e., one partner was infected and one not) were randomized to receive antiretroviral treatment right away